Yin Chao Wu

2 weeks ago | mdpi.com | Guangpeng Zhang |Li Zhang |Alim Samat |Yin Chao Wu

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Jan 9, 2025 | nature.com | Dhruva Biswas |Yun-Hsin Liu |Javier Herrero |Yin Chao Wu |David Moore |Takahiro Karasaki | +18 more

AbstractHuman tumors are diverse in their natural history and response to treatment, which in part results from genetic and transcriptomic heterogeneity. In clinical practice, single-site needle biopsies are used to sample this diversity, but cancer biomarkers may be confounded by spatiogenomic heterogeneity within individual tumors.

Dec 12, 2024 | mdpi.com | Yin Chao Wu

5.1. Random PositionWe randomly generated 50 positions within a 50 m × 50 m range. Each algorithm was run 50 times at each position. Statistical analysis was performed based on the obtained results, with the error distribution of each algorithm shown in Figure 10. Different algorithms exhibited significant differences in positioning accuracy. The Adaptive Bat Optimization Algorithm (ASBOA) had the smallest average error of 0.47 m, indicating its high average positioning precision.

Apr 18, 2024 | dx.doi.org | Yin Chao Wu |Yan Sun

Jan 18, 2024 | onlinelibrary.wiley.com | Ying Liu |Yin Chao Wu |Yang Ji |Botao Zhao

Background Quantitative in-situ pH mapping of gliomas is important for therapeutic interventions, given its significant association with tumor progression, invasion, and metastasis. Although chemical exchange saturation transfer (CEST) offers a noninvasive way for pH imaging based on the pH-dependent exchange rate (ksw), the reliable quantification of ksw in glioma remains constrained due to technical challenges.