Brett McKinnon

Mar 13, 2023 | mdpi.com | Sohye Yoon |Joanna Crawford |Brett McKinnon

Dear Colleagues,The human endometrium is unique because it is a highly regenerative tissue and heals without scarring. Menstruation generates not only pain but also, via retrograde menstruation, contributes to endometriosis. Although Sampson’s implantation hypothesis is generally accepted as the most likely cause of endometriosis, more hypotheses, such as inflammation, hypoxia etc., are needed to explain why only a minor fraction of women get the disease.