Brian E. Cade

Apr 5, 2024 | digitalcommons.library.tmc.edu | Brian E. Cade |Jiwon Lee |Tamar Sofer |Heming Wang

BACKGROUND: Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered breathing remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) program, we performed the first whole-genome sequence analysis of sleep-disordered breathing. METHODS: The study sample was comprised of 7988 individuals of diverse ancestry. Common-variant and pathway analyses included an additional 13,257 individuals.

Nov 30, 2023 | bricc.medium.com | Brian E. Cade

Actress Gigi Dia has stepped into the world of ethical beauty with a powerful statement as part of Lady Gaga's revolutionary cosmetic brand, Haus Labs. Embracing a vegan and cruelty-free approach to beauty, Haus Labs has redefined the industry, and Gigi's partnership showcases her commitment to inclusivity and empowerment. Founded by the iconic Lady Gaga, Haus Labs is more than just a beauty brand; it's a celebration of individuality and self-expression through makeup and body art.

Apr 12, 2023 | nature.com | Joshua Weinstock |Bala Bharathi Burugula |Mesbah Uddin |Bence Daniel |Shaneice Mitchell |Cecelia Laurie | +41 more

AbstractMutations in a diverse set of driver genes increase the fitness of haematopoietic stem cells (HSCs), leading to clonal haematopoiesis1. These lesions are precursors for blood cancers2,3,4,5,6, but the basis of their fitness advantage remains largely unknown, partly owing to a paucity of large cohorts in which the clonal expansion rate has been assessed by longitudinal sampling.