Brian Gordon

2 months ago | nature.com | Jorge J. Llibre-Guerra |Nelly Joseph-Mathurin |Kathleen Carter |Eric McDade |Brian Gordon |Alan E. Renton | +8 more

AbstractWe conducted an in-depth longitudinal study on an individual carrying the presenilin 2 p.Asn141Ile mutation, traditionally associated with dominantly inherited Alzheimer’s disease (AD), who has remarkably remained asymptomatic past the expected age of clinical onset. This study combines genetic, neuroimaging and biomarker analyses to explore the underpinnings of this resilience.

Nov 17, 2024 | nature.com | Stephan A. Kaeser |Christian la Fougère |Jonathan Voglein |Johannes Levin |Nick Fox |Henrik Zetterberg | +16 more

AbstractDisease-modifying therapies for Alzheimer’s disease (AD) are likely to be most beneficial when initiated in the presymptomatic phase. To track the benefit of such interventions, fluid biomarkers are of great importance, with neurofilament light chain protein (NfL) showing promise for monitoring neurodegeneration and predicting cognitive outcomes.

Nov 17, 2024 | nature.com | Stephan A. Kaeser |Christian la Fougère |Jonathan Voglein |Johannes Levin |Nick Fox |Henrik Zetterberg | +16 more

AbstractDisease-modifying therapies for Alzheimer’s disease (AD) are likely to be most beneficial when initiated in the presymptomatic phase. To track the benefit of such interventions, fluid biomarkers are of great importance, with neurofilament light chain protein (NfL) showing promise for monitoring neurodegeneration and predicting cognitive outcomes.

Jul 12, 2023 | jdsupra.com | Brian Gordon

Back in May, New York's Governor Kathy Hochul signed budget legislation increasing the NY minimum wage beginning January 1, 2024, and continuing through 2026. Further, as part of the legislation,...

Apr 20, 2023 | jdsupra.com | Brian Gordon |María Navarro |Patrick Rowe

During this session, the panelists discussed the various types of transaction structures and key considerations when building and executing an exit strategy.