Nelly Joseph-Mathurin

2 months ago | nature.com | Jorge J. Llibre-Guerra |Nelly Joseph-Mathurin |Kathleen Carter |Eric McDade |Brian Gordon |Alan E. Renton | +8 more

AbstractWe conducted an in-depth longitudinal study on an individual carrying the presenilin 2 p.Asn141Ile mutation, traditionally associated with dominantly inherited Alzheimer’s disease (AD), who has remarkably remained asymptomatic past the expected age of clinical onset. This study combines genetic, neuroimaging and biomarker analyses to explore the underpinnings of this resilience.

Jul 10, 2023 | nature.com | Nicole McKay |Brian Gordon |Shaney Flores |Nelly Joseph-Mathurin |Clifford R. Jack |Peter Millar | +19 more

All data described in the current resource manuscript are freely available upon completion of a DIAN-OBS Data Request Form. This request procedure allows DIAN to implement a transparent and inclusive data-sharing practice while maximizing confidentiality and security of our participants’ protected personal information. Every submission is reviewed by the DIAN principal investigator as well as relevant DIAN core leaders (that is, the Imaging Core leader).