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1 month ago | 
biorxiv.org | Xianhe Li |Bruna Garcia |Silvia Reato |Irina Rais
AbstractAs large consumers of cellular metabolites, mitochondria are positioned to compete with invading microbes for the nutrients they require to grow. Yet, little is known of whether cells weaponize mitochondrial metabolism during infection. We found that the transcription factor ATF4 activated a mitochondrial metabolic defense based on the essential B vitamin folate.
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Jan 21, 2025 | 
sigma.world | Bruna Garcia
NuxGame, the experienced betting and casino software provider, has revealed its 2024 results, showcasing a year of exceptional achievements across growth, innovation, and industry recognition. The company reported a 59 percent increase in bet placements and a 144 percent rise in its client base compared to 2023, supported by a 62 percent expansion in team size to meet growing demand.
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Jan 21, 2025 | 
sigma.world | Bruna Garcia
John Gordon, CEO of Incentive Games, has officially joined the HotTakes team as a strategic advisor, ahead of their highly anticipated US launch. HotTakes, a leading B2C Free-to-Play sports prediction app with a strong affiliate network, has achieved rapid growth in the Canadian market and is poised for major expansion with their upcoming launch in the United States.
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Jan 16, 2025 | 
sigma.world | Jenny Ortiz |Bruna Garcia
Tiger Resort Leisure and Entertainment Inc. (TRLEI), the operator of Okada Manila, reported a 3.7 percent year-on-year decline in gross gaming revenue (GGR) for the fourth quarter of 2024. The figure reached PHP8.98 billion (€149.3 million), primarily due to a downturn in the VIP table games segment. However, this showed a 9.1 percent improvement compared to the previous quarter.
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Jan 16, 2025 | 
sigma.world | Neha Soni |Bruna Garcia
Macau’s Galaxy Entertainment Group (GEG) has announced that it will hike salaries for all eligible employees at the senior manager grade and below, effective from April 1. About 98 percent of Galaxy’s staff is set to benefit from the hike. Qualified staff who joined the company before January this year will receive a salary hike according to the programme.
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Jan 15, 2025 | 
sigma.world | Neha Soni |Bruna Garcia
Macau’s casino regulator, the Gaming Inspection and Coordination Bureau (DICJ), will be adding 65 staff in 2025, with most of the newcomers in ‘inspector’ roles. This is part of Legislative Assembly report on Macau’s financial-year 2025 budget plan. The report outlines the explanation to the assembly of the government’s expected revenue and public spending items for this year. However, the report did not mention the current total number of employees of the Macau casino regulator.
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Jan 14, 2025 | 
sigma.world | Bruna Garcia |Neha Soni
Cherry Play, a new and exciting game studio, has broken cover with the appointment of Olga Bajela as Chief Executive Officer. Bajela’s rise through the industry has been meteoric – in just four years she has gone from executive to Chief Commercial Officer of Stakelogic and now CEO of Cherry Play. This rapid rise through the ranks has seen her pick up several industry awards, including Woman Leader of the Year.
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Jan 13, 2025 | 
sigma.world | Bruna Garcia
WA.Technology, the award-winning B2B iGaming solutions provider, has announced that Dave Hickey, Director of Sports Operations, has been promoted to Commercial Director. This strategic appointment highlights WA.Technology’s commitment to strengthening its leadership team as it continues to drive growth in emerging markets and expand its footprint globally.
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Jan 13, 2025 | 
sigma.world | Bruna Garcia
Sports Information Services (SIS), the leading multi-content supplier of 24/7 live betting services, has appointed experienced iGaming executive Harry Heynes in the newly created role of Head of New Business. Heynes is tasked with further broadening the supplier’s commercial reach as it continues to expand its global horizons and product portfolio while working alongside industry-leading technical service providers, including Genius Sports, Playtech, EveryMatrix and Altenar.
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Jan 12, 2025 | 
sigma.world | Jenny Ortiz |Bruna Garcia
Las Vegas Sands Corporation will pay an additional $1 billion to the Singapore Tourism Board (STB) for changes to the Marina Bay Sands (MBS) expansion project. According to the company’s filing, this agreement follows revisions to the project’s design and floor area allocations. The latest payment builds on an initial $963 million premium made in 2019 for leasing the land parcels until August 2066. The expansion project, MBS IR2, has included several enhancements since its original announcement.
