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2 weeks ago | 
acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin
Despite the inroads made in improving treatments for a wide range of cancers, researchers are coming to grips with the unsettling realization that malignant cells still have a surprising number of escape routes. Block one, and another seems to open up.
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1 month ago | 
the-rheumatologist.org | Bryn Nelson
Based on decades of data from dietary and other lifestyle interventions, doctors have long known that significant weight loss can be an effective treatment for people who are overweight and have knee osteoarthritis (OA). One meta-analysis showed that OA pain, function and stiffness scores improved by 2% for every 1% in lost weight.1But the disease can present a catch-22.
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2 months ago | 
acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin
Physicians have long observed that patients who have cancer and are also malnourished are more likely to die. Beyond making treatments less effective and more toxic, malnutrition can reduce a patient’s functional abilities and quality of life while increasing the risk of complications. For many decades, however, the surprisingly common and largely unresolved phenomenon of malnutrition in patients with cancer was seen as an inevitability.
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Jan 20, 2025 | 
acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin
In 2023, the United States set a record for organ transplants, with more than 46,00 transplants performed with organs procured from more than 16,000 deceased donors and nearly 7000 living ones.1 With this encouraging trend reported by the Organ Procurement and Transplantation Network (OPTN), though, experts have stressed that the lifesaving operations can carry a tradeoff.
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Jan 13, 2025 | 
geneticliteracyproject.org | Bryn Nelson
GLP Policy & Performance Review, Fall 2024 The GLP is committed to full transparency. Download the report.
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Jan 7, 2025 | 
technologyreview.jp | Bryn Nelson
How poop could help feed the planet ヒトと家畜の排泄物を安全に処理して農業向けの肥料を製造するテクノロジーは、有機廃棄物を削減すると同時に、世界の増え続ける食料需要を満たすための有効な解決策になるだろう。 by Bryn Nelson2025.01.08 0 シアトル郊外に新設された工業施設からは、未来のテクノロジーの香りがする。この施設では、ヒトや家畜の排泄物を安全に処理し、全米の農地で逼迫しつつある農業に不可欠な栄養分をリサイクルしている。 1ヘクタール弱の工場内には、かすかなアンモニア臭が漂う。巨大な回転スピンドルが、地元の下水処理施設から運び込まれた高温の汚泥を、あるエンジニアが「うんちクレープ（poop crepes）」と呼ぶものに加工している。焼成されたバイオ物質は、特大のスクレーパーを使ってコンベアベルト兼乾燥機に乗せられ、こうして大量の無菌肥料が得られる。この排泄物処理技法は、初期工程で生み出された圧縮蒸気を再利用するため、消費電力を95%削減できる。このプロセスからは乾燥肥料のほかに、ほぼ純粋なアンモニアと水が得られる。...
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Oct 8, 2024 | 
the-rheumatologist.org | Bryn Nelson
Brian McCabe, MD, an otolaryngologist at the University of Iowa, Iowa City, was puzzled. A patient who had undergone surgery to remove diseased cells in the mastoid bones behind both ears returned to have the structures cleaned. In the intervening weeks, however, the patient’s hearing loss had rapidly progressed until the individual was deaf in both ears. In the process of cleaning one of the patient’s mastoids, Dr. McCabe saw an unusual lesion; a biopsy was consistent with vasculitis.
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Jun 17, 2024 | 
the-rheumatologist.org | Bryn Nelson
In 2022, an international group of researchers reported the seminal finding that a gain-of-function variant of a single-stranded ribonucleic acid (RNA) sensor, known as toll-like receptor 7 (TLR7), can cause human systemic lupus erythematosus (SLE).1 The paper in Nature showed that a newly described variant of TLR7, identified in a child with severe lupus, was sufficient to cause lupus in mice.
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May 24, 2024 | 
scientificamerican.com | Bryn Nelson
The U.S. is bracing for another summer of powerful storms and wildfires, on the heels of an and spring, and the monthly shattering of ocean heat records. Beyond the now-annual threat of smoke that last year blanketed the nation, a thickening haze of lies also looms—about everything from and wildfire smoke to abortion and racism.
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Apr 29, 2024 | 
bignewsnetwork.com | Bryn Nelson
At the Fernhill Wetlands along the Pacific Flyway in suburban Forest Grove, Oregon, dedicated birders have documented more than 240 avian species. Uncommon birds like the American bittern and Virginia rail have appeared more frequently on the 90 acres of marshland since it was constructed in 2014. Human visitors have flocked to the picturesque park as well, to sit, walk, watch, and even wed. Not bad for a wastewater treatment plant.
