Bryn Nelson

Seattle

Science Writer and Editor at Freelance

Science writer & author of Flush. No longer active on X due to the aggressive disinformation & anti-Semitism; find me here instead: @seattlebryn.bsky.social

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Articles

New Analysis Reveals More Potential Contributors To Takayasu Arteritis

2 weeks ago | the-rheumatologist.org | Bryn Nelson

The rare systemic inflammatory disease known as Takayasu arteritis primarily targets the aorta and its major branches, such as the carotid arteries that direct oxygenated blood to the brain. Chronic inflammation of the arteries can yield complications, such as aneurysms and stenosis, or a narrowing and blocking of blood vessels that can prevent parts of the body from receiving enough blood and oxygen. This ischemia can lead to tissue damage.
The hidden costs of clinical trials

3 weeks ago | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Amid the intense controversy over drastic cuts to the National Institutes of Health (NIH) and its workforce, a hotly contested cap on the NIH’s reimbursement of indirect costs for facilities and administrative expenses is focusing new attention on the financial burden of the institutions and trial participants that make clinical research possible.
Repurposed drugs may lend a new hand as add‐ons to existing cancer treatments

1 month ago | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Despite the inroads made in improving treatments for a wide range of cancers, researchers are coming to grips with the unsettling realization that malignant cells still have a surprising number of escape routes. Block one, and another seems to open up.
Semaglutatide for Patients with Knee Osteoarthritis?

2 months ago | the-rheumatologist.org | Bryn Nelson

Based on decades of data from dietary and other lifestyle interventions, doctors have long known that significant weight loss can be an effective treatment for people who are overweight and have knee osteoarthritis (OA). One meta-analysis showed that OA pain, function and stiffness scores improved by 2% for every 1% in lost weight.1But the disease can present a catch-22.
How an epidemic of untreated malnutrition is worsening cancer

Mar 4, 2025 | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Physicians have long observed that patients who have cancer and are also malnourished are more likely to die. Beyond making treatments less effective and more toxic, malnutrition can reduce a patient’s functional abilities and quality of life while increasing the risk of complications. For many decades, however, the surprisingly common and largely unresolved phenomenon of malnutrition in patients with cancer was seen as an inevitability.
Amid a boom in organ donation, a heightened focus on cancer risk in transplant recipients

Jan 20, 2025 | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

In 2023, the United States set a record for organ transplants, with more than 46,00 transplants performed with organs procured from more than 16,000 deceased donors and nearly 7000 living ones.1 With this encouraging trend reported by the Organ Procurement and Transplantation Network (OPTN), though, experts have stressed that the lifesaving operations can carry a tradeoff.
Poop is helping to feed the world. Really

Jan 13, 2025 | geneticliteracyproject.org | Bryn Nelson

GLP Policy & Performance Review, Fall 2024 The GLP is committed to full transparency. Download the report.
排泄物を宝の山に、循環型農業の大規模化に挑む肥料メーカー

Jan 7, 2025 | technologyreview.jp | Bryn Nelson

How poop could help feed the planet ヒトと家畜の排泄物を安全に処理して農業向けの肥料を製造するテクノロジーは、有機廃棄物を削減すると同時に、世界の増え続ける食料需要を満たすための有効な解決策になるだろう。 by Bryn Nelson2025.01.08 0 シアトル郊外に新設された工業施設からは、未来のテクノロジーの香りがする。この施設では、ヒトや家畜の排泄物を安全に処理し、全米の農地で逼迫しつつある農業に不可欠な栄養分をリサイクルしている。 1ヘクタール弱の工場内には、かすかなアンモニア臭が漂う。巨大な回転スピンドルが、地元の下水処理施設から運び込まれた高温の汚泥を、あるエンジニアが「うんちクレープ（poop crepes）」と呼ぶものに加工している。焼成されたバイオ物質は、特大のスクレーパーを使ってコンベアベルト兼乾燥機に乗せられ、こうして大量の無菌肥料が得られる。この排泄物処理技法は、初期工程で生み出された圧縮蒸気を再利用するため、消費電力を95%削減できる。このプロセスからは乾燥肥料のほかに、ほぼ純粋なアンモニアと水が得られる。...
Making Sense of Autoimmune Sensorineural Hearing Loss

Oct 8, 2024 | the-rheumatologist.org | Bryn Nelson

Brian McCabe, MD, an otolaryngologist at the University of Iowa, Iowa City, was puzzled. A patient who had undergone surgery to remove diseased cells in the mastoid bones behind both ears returned to have the structures cleaned. In the intervening weeks, however, the patient’s hearing loss had rapidly progressed until the individual was deaf in both ears. In the process of cleaning one of the patient’s mastoids, Dr. McCabe saw an unusual lesion; a biopsy was consistent with vasculitis.
Noncoding Self-RNA Implicated in Lupus Development

Jun 17, 2024 | the-rheumatologist.org | Bryn Nelson

In 2022, an international group of researchers reported the seminal finding that a gain-of-function variant of a single-stranded ribonucleic acid (RNA) sensor, known as toll-like receptor 7 (TLR7), can cause human systemic lupus erythematosus (SLE).1 The paper in Nature showed that a newly described variant of TLR7, identified in a child with severe lupus, was sufficient to cause lupus in mice.