William C. Faquin

3 weeks ago | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Amid the intense controversy over drastic cuts to the National Institutes of Health (NIH) and its workforce, a hotly contested cap on the NIH’s reimbursement of indirect costs for facilities and administrative expenses is focusing new attention on the financial burden of the institutions and trial participants that make clinical research possible.

1 month ago | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Despite the inroads made in improving treatments for a wide range of cancers, researchers are coming to grips with the unsettling realization that malignant cells still have a surprising number of escape routes. Block one, and another seems to open up.

Mar 4, 2025 | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

Physicians have long observed that patients who have cancer and are also malnourished are more likely to die. Beyond making treatments less effective and more toxic, malnutrition can reduce a patient’s functional abilities and quality of life while increasing the risk of complications. For many decades, however, the surprisingly common and largely unresolved phenomenon of malnutrition in patients with cancer was seen as an inevitability.

Jan 20, 2025 | acsjournals.onlinelibrary.wiley.com | Bryn Nelson |William C. Faquin

In 2023, the United States set a record for organ transplants, with more than 46,00 transplants performed with organs procured from more than 16,000 deceased donors and nearly 7000 living ones.1 With this encouraging trend reported by the Organ Procurement and Transplantation Network (OPTN), though, experts have stressed that the lifesaving operations can carry a tradeoff.