Byrd A.L

Aug 22, 2023 | cell.com | Byrd A.L |Michael Williams |Michelle D. Bagood

Highlights•S. epidermidis phenol-soluble modulins promote cytokine expression by keratinocytes•S. epidermidis PSMs with EcpA induce murine Type 17 skin inflammation•S. epidermidis PSM levels are elevated in human atopic dermatitisSummaryStaphylococcus epidermidis is a common microbe on human skin and has beneficial functions in the skin microbiome. However, under conditions of allergic inflammation, the abundance of S. epidermidis increases, establishing potential danger to the epidermis.