Caroline Bass

Featured in: Favicon

Articles

Decoding mesolimbic dopamine transmission in the olfactory tubercle and its contribution to methamphetamine responses through neurochemical sensing and chemogenetics

Nov 14, 2024 | biorxiv.org | Rohan V. Bhimani |Ryan Pauly |Caroline Bass |Jinwoo Park

AbstractCentral dopamine (DA) innervation of the olfactory tubercle (OT) from the ventral tegmental area (VTA) plays a critical role in encoding multisensory information and generating behavioral outputs necessary for survival. However, due to anatomical restrictions and the neurochemical heterogeneity of the VTA and OT, very little is known about the functional link between mesolimbic VTA-DA transmission in the OT and its role in mediating reward and drug seeking.
Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction - Nature Communications

Nov 20, 2023 | nature.com | Sachin Patel |Caroline Bass

AbstractBrain levels of the endocannabinoid 2-arachidonoylglycerol (2-AG) shape motivated behavior and nucleus accumbens (NAc) dopamine release. However, it is not clear whether mobilization of 2-AG specifically from midbrain dopamine neurons is necessary for dopaminergic responses to external stimuli predicting forthcoming reward.

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.