Carsten Joern Beese

Jan 6, 2025 | dx.doi.org | David Bushiri Pwesombo |Carsten Joern Beese |Christopher Schmied |Han Sun

1. IntroductionClick to copy section linkSection link copied!The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.

Jan 6, 2025 | pubs.acs.org | David Bushiri Pwesombo |Carsten Joern Beese |Christopher Schmied |Han Sun

1. IntroductionClick to copy section linkSection link copied!The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.

Oct 29, 2024 | biorxiv.org | Carsten Joern Beese |Christopher Schmied |Han Sun |David Bushiri Pwesombo

AbstractMorphological profiling has recently demonstrated remarkable potential for identifying the biologi-cal activities of small molecules. Alongside the fully supervised and self-supervised machine learn-ing methods recently proposed for bioactivity prediction from Cell Painting image data, we intro-duce here a semi-supervised contrastive (SemiSupCon) learning approach.