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Jan 7, 2025 | 00365-6?rss=yes&sz=64)
cell.com | Jessica D. Ewald |Yao Lu |Cara E. Ellis |Jessica Worton |Jelena Kolic |Shugo Sasaki | +25 more
ForumVolume 37, Issue 1p7-11 1Institute of Parasitology, McGill University, Montreal, QC, Canada 2Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA 3Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada 4Department of Pharmacology, University of Alberta, Edmonton, AB, Canada 5Department of Surgery, University of Alberta, Edmonton, AB, Canada 6Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia,...
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Jan 7, 2025 | cell.com | Jessica D. Ewald |Yao Lu |Cara E. Ellis |Jessica Worton |Jelena Kolic |Shugo Sasaki | +25 more
ForumVolume 37, Issue 1p7-11 1Institute of Parasitology, McGill University, Montreal, QC, Canada 2Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA 3Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada 4Department of Pharmacology, University of Alberta, Edmonton, AB, Canada 5Department of Surgery, University of Alberta, Edmonton, AB, Canada 6Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia,...
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Jan 6, 2025 | 
dx.doi.org | Xiaolu Li |Martin Kaupp |Han Sun |Anton Florian Ketzel
1. IntroductionClick to copy section linkSection link copied!Anisotropic nuclear magnetic resonance (NMR) spectroscopy in solution has been proven for over three decades to provide invaluable structural and dynamic information about biomolecules, particularly proteins and nucleic acids.
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Jan 6, 2025 | 
dx.doi.org | David Bushiri Pwesombo |Carsten Joern Beese |Christopher Schmied |Han Sun
1. IntroductionClick to copy section linkSection link copied!The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.
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Jan 6, 2025 | 
pubs.acs.org | David Bushiri Pwesombo |Carsten Joern Beese |Christopher Schmied |Han Sun
1. IntroductionClick to copy section linkSection link copied!The Cell Painting (CP) assay is a high-content screening method that enables an unbiased and high-throughput evaluation of pharmacological similarity among compounds by comparing the drug-induced morphological changes on cells.
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Nov 27, 2024 | 
mdpi.com | Chang Li |Fanhong Kong |Lei Feng |Han Sun
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Nov 25, 2024 | 
link.springer.com | Han Sun |Yong Jun Jin
AbstractEarly diagnosis of Nonalcoholic steatohepatitis (NASH) is crucial to prevent its progression to hepatocellular carcinoma, but its gold standard diagnosis still requires invasive biopsy. Here, a new marker-based noninvasive chemical biopsy approach is introduced that uses urine-secreted tyrosine metabolites.
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Oct 29, 2024 | 
biorxiv.org | Carsten Joern Beese |Christopher Schmied |Han Sun |David Bushiri Pwesombo
AbstractMorphological profiling has recently demonstrated remarkable potential for identifying the biologi-cal activities of small molecules. Alongside the fully supervised and self-supervised machine learn-ing methods recently proposed for bioactivity prediction from Cell Painting image data, we intro-duce here a semi-supervised contrastive (SemiSupCon) learning approach.
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Oct 24, 2024 | 
mdpi.com | Han Sun |Wenlong Yang |Tianshuo Zhou |Fuye Lu
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Sep 25, 2024 | 
mdpi.com | Han Sun |Gregory Tchou |Nana Liu |Sojin Y. Wass
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
