Caryn Bern

Jan 9, 2025 | digitalcommons.library.tmc.edu | Caryn Bern |Eva Clark |Antonio L Teixeira |María P

KeywordsChagas disease, Chagas cardiomyopathy, Progression, SeverityAbstractChagas disease, the most common form of nonischaemic cardiomyopathy globally, is one of the leading causes of morbidity and mortality in Latin America. Chagas cardiomyopathy has a wide clinical spectrum and prognosis, which is primarily determined by the severity of left ventricular dysfunction. Chagas disease also affects the brain, particularly manifesting as cardioembolic strokes and cognitive impairments.

May 22, 2024 | jamanetwork.com | Eva Clark |Caryn Bern

Approximately 6 million people worldwide, including 300 000 US residents, are infected with Trypanosoma cruzi, the parasite that causes Chagas disease.1 T cruzi is usually transmitted via inoculation of infected feces of blood-feeding triatomine insects through the bite site or intact mucosa. Infected vectors are found throughout continental Latin America and the southern half of the US.