Catharina Maassen

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Substrate elasticity does not impact on DNA methylation changes during differentiation of pluripotent stem cells

Jan 17, 2024 | biorxiv.org | Wolfgang Wagner |Kira Zeevaert |Ann-Christine Henneke |Catharina Maassen

AbstractSubstrate elasticity may direct cell-fate decisions of stem cells. However, it is largely unclear how matrix stiffness impacts on differentiation of induced pluripotent stem cells (iPSCs) and if this is also reflected by epigenetic modifications.

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