Wolfgang Wagner

1 month ago | mdpi.com | Felix Reuß |Mariette Vreugdenhil |Emanuel Bueechi |Wolfgang Wagner

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Felix Reuß *, Mariette Vreugdenhil, Emanuel Bueechi and Wolfgang Wagner Department of Geodesy and Geoinformation, Technische Universität Wien, 1040 Vienna, Austria *Author to whom correspondence should be addressed.

2 months ago | nature.com | Wolfgang Wagner

The aging process is influenced by several factors, including the accumulation of mutations and the acquisition of epigenetic alterations throughout life. A recent study by Koch and colleagues demonstrates that these seemingly independent mechanisms interact: somatic mutations affect DNA methylation and epigenetic age predictions.

Jan 22, 2025 | mdpi.com | Claudio Navacchi |Felix Reuß |Wolfgang Wagner

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Aug 5, 2024 | nature.com | Julia Majewska |Avi Mayo |Wolfgang Wagner |Ido Amit

AbstractThe accumulation of senescent cells promotes ageing and age-related diseases, but molecular mechanisms that senescent cells use to evade immune clearance and accumulate in tissues remain to be elucidated. Here we report that p16-positive senescent cells upregulate the immune checkpoint protein programmed death-ligand 1 (PD-L1) to accumulate in ageing and chronic inflammation.

May 25, 2024 | mdpi.com | Wolfgang Wagner |Klaus Hünting |Siriwan D. Martens |Mariana Schneider

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.