Cecilia Noecker

Jul 2, 2024 | nature.com | Cecilia Noecker |Peter J. Turnbaugh

AbstractThe human gut microbiome vastly extends the set of metabolic reactions catalysed by our own cells, with far-reaching consequences for host health and disease. However, our knowledge of gut microbial metabolism relies on a handful of model organisms, limiting our ability to interpret and predict the metabolism of complex microbial communities.

May 19, 2023 | journals.plos.org | Cecilia Noecker |Juan Sanchez |Juan Sánchez |Chan Zuckerberg Biohub

Comparison of E. lenta’s metabolic profile in vitro and in vivo identifies shared signatures and usage of a novel nutrientHaving characterized the metabolic profile of the E. lenta species in a simplified in vitro environment, we next asked how these findings compare with its metabolic activity in a host, and whether our in vitro platform could help identify metabolic processes performed by E. lenta within the gastrointestinal tract. We monocolonized germ-free (GF) mice with one of 3 strains of E.