Charlotte de Vries

1 month ago | onlinelibrary.wiley.com | Wenqi Huang |Charlotte de Vries |Ravi Sharma

1 Introduction B cells are key players in numerous autoimmune and chronic inflammatory diseases associated with autoantibodies and MHC class II genetic predisposition, which is also underscored by the efficacy of B cell targeted therapy [1], Notably, B cells can influence autoimmune diseases through the production of autoantibodies and cytokines as well as via antigen presentation and subsequent T cell activation.

2 months ago | onlinelibrary.wiley.com | Charlotte de Vries |Wenqi Huang |Ravi Sharma |Kittikorn Wangriatisak

1 Introduction B cells are regarded as central in rheumatoid arthritis (RA), based on the efficacy of B-cell depleting therapies [1], and the hallmark presence of anti-citrullinated protein autoantibodies (ACPA) and rheumatoid factor (RF) in about two-thirds of RA patients. The autoantibody-positive group, referred to as seropositive, is characterized by a more severe disease course, indicating a pathogenic role for autoreactive B cells in RA.

Jan 18, 2025 | myprivacy.dpgmedia.nl | Charlotte de Vries

Jan 11, 2025 | myprivacy.dpgmedia.nl | Charlotte de Vries

Dec 26, 2024 | myprivacy.dpgmedia.nl | Charlotte de Vries