Chee Y. Ooi

Aug 7, 2024 | onlinelibrary.wiley.com | Nicole Green |Christopher Chan |UNSW Medicine |Chee Y. Ooi

1 INTRODUCTION Cystic fibrosis (CF) is a heritable disease caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein.1 CFTR is expressed throughout the pancreatic duct, and hepatobiliary and gastrointestinal (GI) tracts, where dysfunction contributes to the altered intestinal environment and GI symptoms that represent a significant source of morbidity for people with CF (pwCF).