Cheng-I Jonathan Ma

Sep 26, 2024 | biorxiv.org | Cheng-I Jonathan Ma |Weixiang Wang |Frederick R. Maxfield |Noah Steinfeld

AbstractThe recruitment of macrophages to the intima of arteries is considered a critical event in atherosclerotic progression. These macrophages accumulate excessive lipid droplets and become apoptotic foam cells, a hallmark of atherosclerosis. Most studies focus on lipid accumulation through macrophage interaction with modified monomeric LDL. However, in the intima, macrophages predominantly encounter aggregated LDL (agLDL) species.

Jul 30, 2023 | biorxiv.org | Julie Brill |Cheng-I Jonathan Ma

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