Cheng Zhan

Dec 16, 2024 | pubs.rsc.org | Cheng Zhan

Revisiting the Oxygen Reduction Reaction Activity of Two-Dimensional TM-C2N Electrocatalysts via Constant-Potential Density Functional Theory: Crucial Impact of Spin State and Coordination Single atom catalysts (SACs) have shown great potentiality in catalyzing the oxygen reduction reaction (ORR) in fuel cell batteries.

Aug 28, 2024 | nature.com | Ichitaro Abe |JING CHEN |Linna Zhou |Noelia Martínez-Sánchez |Michael L. Dustin |Cheng Zhan | +5 more

AbstractHuman mutations in neuropeptide Y (NPY) have been linked to high body mass index but not altered dietary patterns1. Here we uncover the mechanism by which NPY in sympathetic neurons2,3 protects from obesity.

Jun 2, 2024 | nature.com | Cheng Zhan

AbstractFerroptosis, a type of iron-dependent non-apoptotic cell death, plays a vital role in both tumor proliferation and resistance to chemotherapy. Here, our study demonstrates that MAX’s Next Tango (MNT), by involving itself in the spermidine/spermine N1-acetyltransferase 1 (SAT1)-related ferroptosis pathway, promotes the proliferation of lung adenocarcinoma (LUAD) cells and diminishes their sensitivity to chemotherapy.

Sep 13, 2023 | dx.doi.org | Wei Guo |Chaochao Dun |Feipeng Yang |Cheng Zhan

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May 29, 2023 | nature.com | Cheng Zhan

AbstractFerroptosis, an iron-dependent non-apoptotic cell death, has been shown to play a vital role in tumor proliferation and chemotherapy resistance. Here, we report that KLF11 inhibits lung adenocarcinoma (LUAD) cell proliferation and promotes chemotherapy sensitivity by participating in the GPX4-related ferroptosis pathway.