Chengcheng Huang

Jan 13, 2025 | biorxiv.org | Michael Leone |Chengcheng Huang |Brent Doiron |Carnegie Mellon

AbstractSynaptic physiology is highly stochastic in the neocortex: immediately following an action potential, individual synapses release neurotransmitter unreliably, sometimes even failing to release any vesicles. However, theoretical models of neuronal networks typically neglect this well-established feature of biology, especially recurrent networks.

Aug 24, 2024 | biorxiv.org | Madeline Edwards |Jonathan Rubin |Chengcheng Huang

AbstractSeveral inhibitory interneuron subtypes have been identified as critical in regulating sensory responses. However, the specific contribution of each interneuron subtype remains uncertain. In this work, we explore the contributions of cell-type specific activity and synaptic connections to dynamics of a spatially organized spiking neuron network.