Chie Araki

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Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells

Feb 14, 2023 | biorxiv.org | Yuya Kondo |Nobuyuki Okahashi |Tomoki Shima |Chie Araki

New Results doi: https://doi.org/10.1101/2021.11.16.468557 AbstractAdenosine triphosphate (ATP) regeneration by substrate-level phosphorylation is a general feature of cancer metabolism, even under normoxic conditions (aerobic glycolysis). However, it is unclear why cancer cells prefer inefficient aerobic glycolysis over the highly efficient process of oxidative phosphorylation for ATP regeneration.

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