Chien-Hsien Lai

Dec 7, 2024 | biorxiv.org | Gyeongah Park |Pan Xu |Xiaoqian Sun |Chien-Hsien Lai

AbstractEffective emotional regulation, crucial for adaptive behavior, is mediated by the medial prefrontal cortex (mPFC) via connections to the basolateral amygdala (BLA) and nucleus accumbens (NAc), traditionally considered functionally similar in modulating reward and aversion responses. However, how the mPFC balances these descending pathways to control behavioral outcomes remains unclear.