Gyeongah Park

Dec 7, 2024 | biorxiv.org | Gyeongah Park |Pan Xu |Xiaoqian Sun |Chien-Hsien Lai

AbstractEffective emotional regulation, crucial for adaptive behavior, is mediated by the medial prefrontal cortex (mPFC) via connections to the basolateral amygdala (BLA) and nucleus accumbens (NAc), traditionally considered functionally similar in modulating reward and aversion responses. However, how the mPFC balances these descending pathways to control behavioral outcomes remains unclear.

Jun 1, 2024 | biorxiv.org | Pan Xu |Gyeongah Park |Xiaoqian Sun |Qian Ge

AbstractEmotion regulation, essential for adaptive behavior, depends on the brain's capacity to process a range of emotions. Current research has largely focused on individual emotional circuits without fully exploring how their interaction influences physiological responses or understanding the neural mechanisms that differentiate emotional valence.

Sep 3, 2023 | biorxiv.org | Gyeongah Park |Zhen Jin |Qian Ge

AbstractNeuronal activity promotes high-grade glioma progression via secreted proteins and neuron-to-glioma synapses, and glioma cells boost neuronal activity to further reinforce the malignant cycle. Whereas strong evidence supports that the activity of neuron-to-glioma synapses accelerates tumor progression, the molecular mechanisms that modulate the formation and function of neuron-to-glioma synapses remain largely unknown.