Chin-Hsien Lin

Dec 12, 2023 | nature.com | Chao Deng |Chin-Hsien Lin |Bin Xiao |Eng-King Tan

AbstractRetinal thickness is related to Parkinson’s disease (PD), but its association with the severity of PD is still unclear. We conducted a Mendelian randomized (MR) study to explore the association between retinal thickness and PD.

Aug 25, 2023 | nature.com | Chin-Hsien Lin |Alice Yu

AbstractCRISPR-Cas9 genome editing has promising therapeutic potential for genetic diseases and cancers, but safety could be a concern. Here we use whole genomic analysis by 10x linked-read sequencing and optical genome mapping to interrogate the genome integrity after editing and in comparison to four parental cell lines.