Chun Lin Wu

May 16, 2024 | onlinelibrary.wiley.com | Yunxia Wang |Jiajia Yang |Chun Lin Wu |Yuqin Guo

1 INTRODUCTION Diabetic nephropathy (DN), a serious microvascular complication of diabetes mellitus, affects approximately 50% of patients with both type I and type II diabetes.1, 2 DN is characterized by extracellular matrix accumulation, basement membrane thickening, and glomerular hypertrophy, which are related to glomerular mesangial cell proliferation.3 Hyperglycemic factors including terminal glycosylation products contribute to excess extracellular matrix and lead to renal fibrosis.4...

Mar 2, 2023 | bcg.com | Wen Xie |Chun Lin Wu

By Sven Fraterman, , Chun Wu, , and  Reading time: 12 min Key Takeaways The biopharmaceutical industry is undergoing a revolution in oncology and other complex disease areas, thanks to a wave of innovation leading to new drug modalities. These emerging technologies will create unprecedented opportunities for the biopharmaceutical firms that actively pursue them, yet they also present new risks.