Claire Simon

Jan 8, 2025 | cell.com | Georgia Lea |Paula Doria-Borrell |Ana Ferrero-Micó |Anakha Varma |Claire Simon |Holly Anderson | +8 more

IntroductionThe isolation and culture of human embryonic stem cells (hESCs) has been invaluable in building our understanding of pluripotency, cell fate commitment, differentiation, epigenetic programming, and gene regulation in human development.1,2 The derivation of the analogous cells for the human placental lineage has taken longer to develop and hence these processes in trophoblast remain less well understood.