-
Jan 19, 2025 | 
tandfonline.com | Thomas Jemielita |Cong Chen
ABSTRACTRandomized clinical trials (RCTs) can benefit from using Real-World Data (RWD) as a supplementary data source to enhance their analysis. An Augmented RCT combines randomized treatment and control groups with synthetic controls derived from RWD. This way, the trial can achieve less prospective enrollment, higher statistical power, and lower costs. However, to ensure scientific validity, the synthetic controls must satisfy the same eligibility criteria as the trial participants.
-
Dec 6, 2024 | 
pubs.rsc.org | Haiyang Wang |Cong Chen |Junxia Shen |Pierre-Yves Olu
Self-supported Ni/NiO heterostructures with a controlled reduction protocol for enhanced industrial alkaline hydrogen evolution†
Self-supported Ni/NiO heterostructures with controllable ratios used in industrial alkaline water electrolysis (AWE) systems lead to an ultralow voltage of 1.79 V at 400 mA cm−2 for 2 weeks, ascribed to the synergic combination of abundant active sites, rapid electron/mass transfer and optimal HER kinetics.
-
Nov 25, 2024 | 
pubs.rsc.org | Haiyang Wang |Cong Chen |Junxia Shen |Pierre-Yves Olu
Self-supported Ni/NiO heterostructures with controlled reduction protocol for enhanced industrial alkaline hydrogen evolution
Self-supported Ni/NiO heterostructures with controllable ratios used in industrial alkaline water electrolysis (AWE) system leads to an ultralow voltage of 1.79 V at 400 mA cm-2 for 2 weeks, ascribed to the synergic combination of abundant active sites, rapid electron/mass transfer and optimal HER kinetics.
-
Nov 13, 2024 | 
mdpi.com | Tianfeng Zhou |Cong Chen |Cong Dong |Qinghua Li
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Oct 19, 2024 | 
biorxiv.org | Cong Chen |Hua-Wei Yi |Yi Zhang |Tong-Yao Gao
AbstractUbiquitin (Ub), a key player of protein turnover, can be phosphorylated by PINK1 kinase to generate S65-phosphorylated ubiquitin (pUb). Elevated pUb levels have been observed in aged and Parkinson's diseases afflicted human brains. However, how pUb is involved in neurodegeneration remains elusive. Here we show that elevation of pUb is pervasive in various neurodegenerative conditions, including Alzheimer's disease, aging, and ischemic injury.
-
Oct 2, 2024 | 
cambridge.org | Hannah Moore |Charlie Turner |Chris Rawlinson |Cong Chen
Risk factors for transmission After adjustment for clinical and personal characteristics (see Table 2), household exposure was estimated to have by far the strongest association with COVID-19 transmission (aOR = 2.64, 95% CI: 1.92–3.63). Of other exposure settings, being a household visitor (aOR = 1.50, CI: 1.09–2.07) or being a contact during travel or commuting (aOR 1.61, CI: 1.08–2.40) were the only settings significantly associated with increased odds of transmission (Table 2).
-
Sep 30, 2024 | 
mdpi.com | Cong Chen |Lin-Lin Zhao |Qin Lang
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Sep 30, 2024 | 
mdpi.com | Cong Chen |Lang Xu |Fanxin Wang |Jiayin Pan
1. IntroductionEstablishing an efficient, reliable, and flexible maritime logistics system has been a focal point for numerous scholars, as maritime transportation plays a crucial role in global trade and supply chain networks. Within this domain, the berth allocation problem (BAP) is a key challenge, as it directly impacts the operational efficiency of ports, which are critical nodes in maritime logistics.
-
Sep 23, 2024 | 
nature.com | Cong Chen |Jing Han |Yu Sun |Jiafu Ji
AbstractHER2(+) gastric cancer (GC) can benefit from trastuzumab. However, the impact of additional trastuzumab in preoperative treatment on immune cells remains largely unknown. In cohort I, immune cells were detected by immunohistochemistry in 1321 patients. Then 88 HER2(+) patients received preoperative therapy were collected as cohort II. Immune cell profiles and changes were analyzed in paired pre- and post-operative specimens using multiple immunohistochemistry staining.
-
Sep 21, 2024 | 
chemistry-europe.onlinelibrary.wiley.com | Cong Chen |Pierre-Yves Olu |Ronglei Fan |Shizi street Suzhou
Hydrogen has been recognized as a green energy carrier, which can relieve energy shortage and environmental pollution. Currently, alkaline water electrolysis (AWE) driven by renewable energy to produce large-scale green hydrogen is a mainstream technology. However, tardy cathodic hydrogen evolution reaction (HER) and stability issue of catalysts make it challenging to meet the industrial requirements.
