Conrad T. Pfeiffer

Aug 13, 2024 | science.org | Annalisa M. VanHook |Xue Jiang |Conrad T. Pfeiffer

Editor’s summaryThe specific patterns of phosphorylation in the intracellular tail of a G protein–coupled receptor (GPCR) are thought to act as a barcode that determines whether G proteins are stimulated or β-arrestins are recruited. Gareri et al. investigated the role of phosphorylation barcodes in signaling by the angiotensin II type 1 receptor (AT1R).