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Dec 21, 2023 | onlinelibrary.wiley.com | Francis Crick |Crown Street

For structural biology practitioners a number of techniques, such as X-ray/neutron/electron crystallography and cryo electron microscopy (cryo-EM), are available to determine the 3D atomic structure of a macromolecular structure. Any one of these techniques can be applied to produce an initial model, comprising atomic positions and their associated uncertainties, which is fitted to the experimental data, such as a set of diffraction intensities or an electrostatic potential map.

Nov 30, 2023 | academic.oup.com | Crown Street

The 31st Nucleic Acids Research database issue, in customary fashion, ranges broadly across biology with a total of 180 papers. Last year's recent record of 90 new databases is matched this year (Table 1) while 83 papers report developments from resources previously covered by NAR. Seven further papers provide updates on databases most recently published elsewhere (Table 2).