D. Comber

Oct 8, 2024 | onlinecjc.ca | S. Dababneh |J. Parker |R. Ahmed |D. Comber |J. Phulka |C. Tsai | +4 more

The development of atrial fibrillation (AF) in patients with non-ischemic cardiomyopathy (NICM), a precursor for heart failure with prominent genetic underpinnings, is associated with poor prognosis. Tools to risk stratify NICM patients for AF remain lacking. With the rise of scientific advancements enabling personalized risk stratification, such as polygenic risk scores and serum proteomics, we sought to employ a proteogenomics approach to improve prediction of AF in patients with NICM.