Daisuke Motooka

Feb 8, 2024 | biorxiv.org | Yoshiaki Yasumizu |Makoto Kinoshita |Martin Zhang |Daisuke Motooka

AbstractMyasthenia gravis (MG) is known to be epidemiologically associated with abnormalities of the thymus, an organ that maintains central tolerance. However, due to the complexity of the thymus, specific characteristics related to the pathogenesis of MG remain elusive. In our study, we attempted to narrow down the features associated with MG using spatial transcriptome analysis of thymoma and thymic hyperplasia samples.