Danhua Su

Dec 10, 2024 | onlinelibrary.wiley.com | Tong Wu |Danhua Su |Lei Zhang |Ting Liu

Objective To explore T cell-intrinsic mechanisms underpinning the mal-differentiation of tissue-resident memory T (Trm) cells in patients with rheumatoid arthritis (RA). Methods Circulating T cells from patient with RA and healthy individuals were used for Trm cell differentiation. The role of Hobit in Trm differentiation was investigated through targeted silencing experiments.