Daniel Armendariz

Denver

Managing Partner at Hispanic Business TV

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Articles

Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes

Nov 20, 2023 | biorxiv.org | Yihan Wang |Daniel Armendariz |Lei Wang |Huan Zhao

AbstractGenetic studies have associated thousands of enhancers with breast cancer. However, the vast majority have not been functionally characterized. Thus, it remains unclear how variant-associated enhancers contribute to cancer. Here, we perform single-cell CRISPRi screens of 3,512 regulatory elements associated with breast cancer to measure the impact of these regions on transcriptional phenotypes.
Limitations of principal components in quantitative genetic association models for human studies

May 3, 2023 | elifesciences.org | Daniel Armendariz
CHD-associated enhancers shape human cardiomyocyte lineage commitment

Apr 24, 2023 | elifesciences.org | Daniel Armendariz
Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules

Nov 26, 2019 | cell.com | Daniel Armendariz

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