Daniel Belsky

Sep 15, 2024 | nature.com | Jesse R. Poganik |Daniel Belsky |Joe LaCroix |Alan Cohen |Steven R. Cummings |Luigi Ferrucci | +15 more

AbstractBiomarkers of aging (BOA) are quantitative parameters that predict biological age and ideally its changes in response to interventions. In recent years, many promising molecular and omic BOA have emerged with an enormous potential for translational geroscience and improving healthspan. However, clinical translation remains limited, in part due to the gap between preclinical research and the application of BOA in clinical research and other translational settings.

Feb 14, 2024 | nature.com | Chiara Herzog |Jesse R. Poganik |Kejun Ying |Daniel Belsky |Albert T. Higgins-Chen |Alan Cohen | +12 more

AbstractThe search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of interventions promoting healthy aging and longevity. However, no consensus exists on how biomarkers of aging should be validated before their translation to the clinic.

Sep 25, 2023 | nature.com | Xu Gao |Yinan Zheng |Daniel Belsky

Correction to: Nature Communications https://doi.org/10.1038/s41467-023-38013-7, published online 20 April 2023The original version of this Article contained an error in the ‘Measurements of covariates’ part of the Methods section, which omitted the following sentence detailing inclusion criteria: ‘Additional participants with ≥140 mmHg SBP and/or ≥90 mmHg SBP at the enrolment were also included as individuals with hypertension at baseline’.

Aug 31, 2023 | cell.com | Universität Innsbruck |Jesse R. Poganik |Jamie Justice |Daniel Belsky

These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.

Apr 20, 2023 | nature.com | Xu Gao |Yinan Zheng |Daniel Belsky

Study design and populationUK Biobank research has received approval from the North West Multicenter Research Ethical Committee. Written informed consent were provided by all participants. UK Biobank is an ongoing prospective study with 502,536 participants recruited in 2006–2010 at the age of 37–73 years (baseline survey) with multiple follow-ups38. At baseline, participants were asked to provide information on their lifestyle and health, and their biological samples were collected.