Dario Tommasini

2 months ago | cell.com | Dario Tommasini |Takeshi Yoshimatsu |Teresa Puthussery |Tom Baden |Karthik Shekhar

1Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA 2Department of Ophthalmology and Visual Sciences, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA 3Vision Sciences Graduate Group, University of California, Berkeley, Berkeley, CA 94720, USA 4Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, CA 94720, USA 5Center for Sensory Neuroscience and Computation, Sussex...

Nov 6, 2024 | biorxiv.org | Dario Tommasini |Takeshi Yoshimatsu |Tom Baden |Karthik Shekhar

AbstractThe tetrapod double cone is a pair of tightly associated cones called the "principal" and the "accessory" member. It is found in amphibians, reptiles, and birds, as well as monotreme and marsupial mammals but is absent in fish and eutherian mammals. To explore the potential evolutionary origins of the double cone, we analyzed single-cell and -nucleus transcriptomic atlases of photoreceptors from six vertebrate species: zebrafish, chicken, lizard, opossum, ground squirrel, and human.