Deguan Lv

Jan 14, 2025 | sciencedirect.com | M.B. El Mdawar |Jessica Waibl Polania |Peter E. Fecci |Deguan Lv

Glioblastoma, the most common primary tumor of the central nervous system (CNS), remain uniformly aggressive and lethal, with a median survival of less than 2 years.1,2,3,4 Glioblastoma stem cells (GSCs) possess the fundamental stem cell properties including self-renewal, multi-potency, and tumor maintenance, and they share other characteristics with normal neural stem cells (NSCs).5,6 Although they comprise a small fraction of total tumor cells, GSCs have been demonstrated to promote tumor...