Del Prato

Aug 1, 2024 | cardiab.biomedcentral.com | Del Prato |Carolyn S P |Baylor Scott

The ARISE-HF trial (NCT 04083339; Date Registered August 23, 2019) is an ongoing phase 3 randomized, placebo-controlled, double-blinded clinical trial that aims to investigate the efficacy of AT-001, an aldose reductase inhibitor, in patients with DbCM, with any prior history of overt HF. All patients provided written, informed consent. All study procedures were approved by individual Institutional Review Boards and the study was conducted in accordance with the Declaration of Helsinki.

May 6, 2024 | eprints.gla.ac.uk | Del Prato

Rutter, M. K. et al. (2024) Indirect effects of the COVID-19 pandemic on diagnosing, monitoring, and prescribing in people with diabetes and strategies for diabetes service recovery internationally. Diabetes Research and Clinical Practice, 212, 111693. (doi: 10.1016/j.diabres.2024.111693) (PMID:38719027) Text326610.pdf - Published Version Available under License Creative Commons Attribution.

Apr 23, 2024 | diabetesjournals.org | Del Prato

At day 3, fasting and mean MMTT glucose levels were lower with SAXA+DAPA (−31.1 ± 1.6 and −91.5 ± 12.4 mg/dL) than with SAXA (−7.1 ± 2.1 and −53 ± 10.5 mg/dL) or DAPA (−17.0 ± 1.1 and −42.6 ± 10.0 mg/dL, respectively; P < 0.001). Insulin secretion rate (SAXA+DAPA +75%; SAXA +11%; DAPA 3%) and insulin sensitivity (+2.2 ± 1.7, +0.4 ± 0.7, and +0.4 ± 0.4 mg ⋅ kg−1⋅ min−1, respectively) improved with SAXA+DAPA (P < 0.007).

Feb 27, 2024 | cardiab.biomedcentral.com | Del Prato |Metabolic Diseases

MG, SDP and GP designed the study, directly accessed and verified the underlying data, drafted the manuscript, approved its final version and take the decision to submit and publish the manuscript; MG, DL and GP contributed to analysis and interpretation of data, revised the article’s intellectual content, and approved its final version; MG, MA, AB, FC, CB, PF and PM acquired data, revised the article’s intellectual content, and approved its final version.

Feb 6, 2024 | eprints.gla.ac.uk | John J.V |Del Prato

Gilbert, M. P., Skelly, J., Hernandez, A. F., Green, J. B., Krychtiuk, K. A., Granger, C. B., Leiter, L. A., McMurray, J. J.V. , Del Prato, S. and Pratley, R. E. (2024) Effect of albiglutide on cardiovascular outcomes in older adults: a post hoc analysis of a randomized controlled trial. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15479) (PMID:38317618) (Early Online Publication)Text319233.pdf - Published Version Available under License Creative Commons Attribution Non-commercial.