Denis J. Ohlstrom

1 month ago | nature.com | Hope Mumme |Chenbin Huang |Denis J. Ohlstrom |Sunil Raikar |Deborah DeRyckere |Christopher Porter | +2 more

AbstractSingle-cell transcriptome profiling enables unparalleled characterization of the heterogeneous microenvironment of pediatric leukemias. To facilitate comparative analyses and generate pediatric leukemia signatures, we collect, process, and annotate single-cell data comprising over 540,000 cells from 159 different pediatric acute leukemia (myeloid, lymphoid, mixed phenotype lineages) and healthy bone marrow (BM) samples, profiled in our lab and curated from publicly available studies.