DongAhn Yoo

2 months ago | nature.com | DongAhn Yoo |Arang Rhie |Prajna hebbar |Francesca Antonacci |Glennis A. Logsdon |Brandon Pickett | +66 more

AbstractThe most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies1,2,3. Consequently, our understanding of the evolution of our species is incomplete. Here we present haplotype-resolved reference genomes and comparative analyses of six ape species: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang.

Jun 6, 2024 | biorxiv.org | Hyeonsoo Jeong |Philip C. Dishuck |DongAhn Yoo |William Harvey

AbstractSegmental duplications (SDs) contribute significantly to human disease, evolution, and diversity yet have been difficult to resolve at the sequence level. We present a population genetics survey of SDs by analyzing 170 human genome assemblies where the majority of SDs are fully resolved using long-read sequence assembly.