Dylan J. Taatjes

2 weeks ago | genomebiology.biomedcentral.com | Taylor Jones |Rutendo F. Sigauke |Lynn Sanford |Dylan J. Taatjes |Mary Allen |Robin Dowell

The stand-alone TF Profiler application can be found on github (https://github.com/Dowell-Lab/TF_profiler) and Zenodo [76]. TF Profiler takes an annotation file for bidirectional regions from a nascent sequencing experiment and derives a TF activity profile. This includes generating simulated sequences based on the base composition of the regions provided, scanning for PSSM hits within the genome and statistically assessing TF enrichment and depletion.