Dylan J. Terstege

Nov 12, 2024 | biorxiv.org | Dylan J. Terstege |Yi Ren |Heewon Seo |Liisa A Galea

AbstractAlzheimer's disease is a debilitating neurodegenerative disorder with no cure and few treatment options. In early stages of Alzheimer's disease, impaired metabolism, and functional connectivity of the retrosplenial cortex strongly predict future cognitive impairments. Therefore, understanding Alzheimer's disease-related deficits in the retrosplenial cortex is critical for understanding the origins of cognitive impairment and identifying early treatment targets.