Easton Ryan

Nov 20, 2024 | onlinelibrary.wiley.com | Lawrence A. Lavery |Arthur Tarricone |Easton Ryan |Peter A. Crisologo

1 INTRODUCTION The global prevalence of diabetes is increasing each year. Diabetic foot ulcers (DFUs) have an annual incidence of 2%–7%,1 and infected DFUs are a major cause of hospitalisation and non-traumatic lower limb amputation.2-5 Among patients with DFUs treated in the outpatient setting, 60% develop infections and 20% of those involve infection of the bone. When infection severity requires hospitalisation, the ratio of soft tissue to bone infection is reversed.

Mar 1, 2024 | onlinelibrary.wiley.com | Lawrence A. Lavery |Mehmet A. Suludere |Peter A. Crisologo |Easton Ryan

AKA above knee amputation BKA below knee amputation CI confidence interval CKD chronic kidney disease CRP C-reactive protein DM diabetes mellitus ESRD end-stage renal disease HbA1c glycosylated haemoglobin IWGDF International Working Group on The Diabetic Foot MRI magnetic resonance imaging OM osteomyelitis OR odds ratio SIRS systemic inflammatory response syndrome SPEC-CT single-positron emission computed tomography STI soft tissue infection WBC white blood cell count 1 INTRODUCTION Persons...