ECCPS Bioinformatics

May 22, 2024 | academic.oup.com | Justus Liebig |Bad Nauheim |Paediatric Urology |ECCPS Bioinformatics

Testicular chemokines and their receptors (especially those essential for trafficking of monocytes) are elevated in orchitis, and activin A modulates the expression of the chemokine/chemokine receptor network to promote monocyte/macrophage and T cell infiltration into the testes, causing extensive tissue damage.