Edda Spiekerkoetter

1 month ago | jci.org | Edda Spiekerkoetter |Rahul Kumar |Qadar Pasha |Brian Graham

AbstractPulmonary hypertension (PH) encompasses a heterogenous group of disorders with the common feature of increased pulmonary arterial pressures. Patients with PH associated with lung disease and/or hypoxia undergo immune-mediated vascular remodeling that includes thickening of the muscular layer surrounding arteries and arterioles. In this issue of the JCI, Kumar and colleagues examined the role of interstitial macrophages in a model of high-altitude PH.