Brian Graham

1 month ago | jci.org | Edda Spiekerkoetter |Rahul Kumar |Qadar Pasha |Brian Graham

AbstractPulmonary hypertension (PH) encompasses a heterogenous group of disorders with the common feature of increased pulmonary arterial pressures. Patients with PH associated with lung disease and/or hypoxia undergo immune-mediated vascular remodeling that includes thickening of the muscular layer surrounding arteries and arterioles. In this issue of the JCI, Kumar and colleagues examined the role of interstitial macrophages in a model of high-altitude PH.

Sep 10, 2024 | americanbanker.com | Brian Graham |Klaros Group

In late July, on a party-line vote, the Federal Deposit Insurance Corp. proposed to expand the definition of a "brokered deposit," reversing (and then some) a narrower definition also adopted by party-line vote during the previous administration.

Sep 10, 2024 | today.westlaw.com | Brian Graham

In late July, on a party-line vote, the Federal Deposit Insurance Corp. proposed to expand the definition of a "brokered deposit," reversing (and then some) a narrower definition also adopted by party-line vote during the previous administration. At...

Jun 7, 2024 | onlinelibrary.wiley.com | Brian J. Levandowski |Brian Graham |Nile Abularrage |Ronald T. Raines

1 INTRODUCTION 5-Membered dienes such as 4H-pyrazoles are rapidly emerging as useful click reagents.1, 2 Spirocyclization provides an effective means to increase the Diels–Alder reactivity of 4H-pyrazoles by circumventing the disrupting effects of geminal repulsion in acyclic geminally substituted 5-membered dienes.3-6 Although 4H-pyrazoles containing five-membered spirocycles have been previously synthesized, they are predicted to be less reactive as Diels–Alder dienes than four-membered...

May 2, 2024 | americanbanker.com | Brian Graham |Klaros Group

On Friday April 26, the FDIC closed Republic First Bank in a failure estimated to cost the deposit insurance fund $667 million. Like other recent failed banks, Republic First's official regulatory capital levels appeared to be in solid shape right up to its collapse.