Eduardo A. Groisman

1 month ago | nature.com | Seth G Kabonick |Kamalesh Verma |Jennifer L Modesto |Victoria Pearce |Eduardo A. Groisman |Kailyn M. Winokur

AbstractHuman dietary choices control the gut microbiome. Industrialized populations consume abundant amounts of glucose and fructose, resulting in microbe-dependent intestinal disorders. Simple sugars inhibit the carbohydrate utilization regulator (Cur), a transcription factor in members of the prominent gut bacterial phylum, Bacteroidetes. Cur controls products necessary for carbohydrate utilization, host immunomodulation, and intestinal colonization.