Edward Curry

Jun 21, 2024 | analyticalsciencejournals.onlinelibrary.wiley.com | Edward Curry |Svetlana E. Sedelnikova |John Rafferty |Martyn Hulley

CGE capillary gel electrophoresis CLuc Cypridina luciferase dsRNA double-stranded RNA IVT in vitro transcription RNAP RNA polymerase 1 INTRODUCTION The clinical success of SARS-Cov-2 vaccines established synthetic mRNA as an effective drug format, paving the way for hundreds of new mRNA-based vaccines and gene therapies to enter clinical trials.[1, 2] This has resulted in a sharp increase in global demand for mRNA production, and shifted mRNA manufacturing from a relatively niche process to...