Elena Kudryashova

Dec 30, 2024 | mdpi.com | Elena Kudryashova

1. IntroductionMacrophages constitute an important component in the immune response to a wide range of conditions, encompassing autoimmune, infectious, inflammation and fibrotic diseases, among others [1,2,3,4,5]. The key mechanism responsible for maintaining tissue integrity and initiating tissue response to injury is the complex activity of tissue macrophages, which remove dying cells and bacteria, as well as produce a wide range of biologically active substances essential for tissue function.

Dec 13, 2024 | mdpi.com | Elena Kudryashova

3. Results and Discussion 3.1. Drug CandidatesTable 2 present the compounds under investigation encompasses a variety of antimicrobial dyes, including “drug candidates” chalcone, stilbenoid, cyano-7-methoxychromene and xanthylium derivatives, R351, as well as antiseptic agents and antibiotics (Table 2).

Nov 9, 2024 | mdpi.com | David Heisler |Elena Kudryashova |Regan Hitt |Blake Williams

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Jul 2, 2024 | biorxiv.org | David Heisler |Elena Kudryashova |Regan Hitt |Blake Williams

AbstractCompetition between bacterial species is a major factor shaping microbial communities. In this work, we explored the hypothesis that competition between bacterial pathogens can be mediated through antagonistic effects of bacterial effector proteins on host systems, particularly the actin cytoskeleton.