Eloïse Dray

May 31, 2024 | nature.com | Melissa L. Folkerts |Eloïse Dray |Weixing Zhao |Nicholas R. Pannunzio

AbstractThe master DNA damage repair histone protein, H2AX, is essential for orchestrating the recruitment of downstream mediator and effector proteins at damaged chromatin. The phosphorylation of H2AX at S139, γH2AX, is well-studied for its DNA repair function. However, the extended C-terminal tail is not characterized.